EVALUATION OF TRANSDERMAL TRANSPORT AND CONCURRENT CUTANEOUS HYDROLYSIS OF TIMOLOL PRODRUG FOR THE TREATMENT OF INFANTILE HEMANGIOMAS

Evaluation of Transdermal Transport and Concurrent Cutaneous Hydrolysis of Timolol Prodrug for the Treatment of Infantile Hemangiomas

Infantile hemangiomas (IH) leave sequelae after involution.Topical application of timolol maleate (TM) is the mainstream treatment for superficial lesions but is limited by its low penetrable properties.We aimed to develop a superior skin permeation drug while maintaining the therapeutic properties of timolol.We predict that this Spray Arm Coupling

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Data assimilation in atmospheric chemistry models: current status and future prospects for coupled chemistry meteorology models

Data assimilation is used in atmospheric chemistry models to improve air quality forecasts, construct re-analyses of three-dimensional chemical (including aerosol) concentrations and perform inverse modeling of input variables or model parameters (e.g., emissions).Coupled chemistry meteorology models (CCMM) are atmospheric chemistry models that sim

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Plague Transmission from Corpses and Carcasses

Knowing whether human corpses can transmit plague will inform policies for handling the bodies of those who have died Spray Arm Coupling of the disease.We analyzed the literature to evaluate risk for transmission of Yersinia pestis, the causative agent of plague, from human corpses and animal carcasses.Because we could not find direct evidence of t

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Classification of Obsessive-Compulsive Disorder Using Distance Correlation on Resting-State Functional MRI Images

Both the Pearson correlation and partial correlation methods have been widely used in the resting-state functional MRI (rs-fMRI) studies.However, they can only measure linear relationship, although partial correlation excludes some indirect effects.Recent distance correlation can discover both the linear and non-linear dependencies.Our goal was to

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